The effect of green robust coffee gel (coffea canephora) to collagen density on gingival wound healing (an in-vivo study in wistar rats)
Objective: This study aims to determine the effect of robusta green coffee gel on the collagen density in Wistar rats. Material and Methods: The subjects were 45 Wistar rats, each wounded with a 3 mm punch biopsy in the mandibular incisor gingiva. The rats were then divided into 5 groups, namely the positive control group (Povidone-iodine 10%), negative control (gel base), and 3 treatment groups (10%, 20%, and 40% concentration of Robusta green coffee gel). The intervention was carried out twice a day. A total of 3 mice in each group were then sacrificed on the 5th and 10th days to see the collagen density using the Mallory Trichrome staining technique. Collagen density was observed using a microscope with 400x magnification in 5 fields of view. Kruskal Wallis test was used for data processing. Results: There was no difference in collagen density regardless of the coffee gel concentration at each observation time, with p>0.05. Conclusion: There was no effect on the times of observation or dose concentration of robusta coffee gel on collagen density on gingival wound healing in Wistar rats.
How to Cite
Suryadewi, N.-P. I. ., Utomo, R. B., & Bramanti, I. . (2023). The effect of green robust coffee gel (coffea canephora) to collagen density on gingival wound healing (an in-vivo study in wistar rats). Journal of Dentomaxillofacial Science, 8(1). https://doi.org/10.15562/jdmfs.v8i1.1435