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A rare case of oral pemphigus vulgaris in teenager suspected induced by stress

Abstract

AbstractObjective : To provide early therapy in teenager pemphigus vulgaris patients so that healing of lesions in the oral cavity is faster.Methods : A 14-year-old boy came to the oral medicine installation RSGM Unpad with complaints of canker sores since 5 days before, initially only at buccal mucosa and treated but multiplied and getting worse. Ulsers like this is the first time experienced by patient. The patient is on antibiotic therapy and is undergoing a national examination. Extra oral examination found dry upper and lower lip, exfoliative and bleeding tendency. Intra-oral examination found ulcer lesions covered with sloughing on the upper and lower labial mucosa, right and left buccal mucosa, and tongue. The dorsum of the tongue has a yellowish white plaque that can be scrapped and does not leave the erythema area. The results of laboratory tests showed an increase in leukocytes, platelets and LEDs while total Ig E was normal. Based on the anamnesis and clinical examination, we diagnosed patient with pemphigus vulgaris. Patient get non-pharmacological therapy, namely oral hygiene instructions (OHI), communication, information, and education (CIE) while pharmacological therapy in the form of dexamethasone, prednisone, vitamin B12 and hyaluronic acid.Results : One month after treatment, the lesions have healed.Conclusion : Appropriate early therapy, good communication, information and education about the lesions in patient with oral pemphigus vulgaris will  relieve stress  and accelerate the process of healing lesions, especially in teenager patient.Keywords : Oral pemphigus vulgaris, stress, teenager
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References

  1. Ariyawardana A, Tilakaratne WM, Dissanayake M, Vitanaarachchi N, Basnayake LK, Sitheeque MAM, et al. Oral pemphigus vulgaris in children and adolescents : a review of the literature and a case report. Int J Paediatr Dent. 2005;15:287–93.
  2. Ljubojevic S, Lipozencic J, Brenner S, Budimcict D. Pemphigus vulgaris : a review of treatment over a 19-year period. JEADV. 2002;16:599–603.
  3. Ferreira JPR, Araujo PC, Saliba MTA, Consolaro RB, Garbin CAS. Pemphigus vulgaris in adolescence : a case report. Int J Odontostomat. 2013;7(2):215–20.
  4. Surya V, Kumar P, Gupta S, Urs A. Childhood pemphigus vulgaris : report of two cases with emphasis on diagnostic approach. Contemp Clin Dent. 2018;S373-376.
  5. Hettiarachchi K, Jayasinghe R, Gunasena C, Jayasooriya PR. Juvenile pemphigus vulgaris as a differential diagnosis for chronic generalized oral ulceration in an adolescent : a case report and a review of literature. Int Journalof Exp Dent Sci. 2018;7(2):143–6.
  6. Pires FR, Ferraz CCR, Alves F de A, Lopes MA, Almeida OP de. Pemphigus vulgaris in adolescence : case report. Am Acad Pediatr Dent. 2000;22(2):159–62.
  7. Dipankar D, Kanwar AJ. Childhood Pemphigus. Indian J Dermatol. 2006;51(2):89–95.
  8. Dagistan S, Goregen M, Milog O, Çakur B. Oral pemphigus vulgaris : a case report with review of the literature. Journ Oral Sci. 2008;50(3):359–62.
  9. Bascones-martinez A, Munoz-corcuera M, Bascones-ilundain C, Esparza-gómez G. Oral manifestations of pemphigus vulgaris : clinical presentation , differential diagnosis and management. J Clin Exp Res. 2010;1(2):2–5.
  10. Ruocco V, Ruocco E, Schiavo A Lo, Brunetti G, Guerrera LP, Wolf R. Pemphigus : Etiology , pathogenesis , and inducing or triggering factors : Facts and controversies. Clin Dermatol. 2013;31(4):374–81.
  11. Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Payne AS, et al. Pemphigus. Dis Prim. 2017;3:1–18.
  12. Scully C, Challacombe SJ. Pemphigus vulgaris : update On etiopathogenesis. Crit Rev Oral Biol Med. 2002;13(5):397–408.
  13. Wardhana M. Psikoneuroimunologi di bidang dermatologi. MDVI. 2011;38(4):175–80.
  14. Tamir A, Ophir J, Brenner S. Pemphigus vulgaris triggered by emotional stress. Dermatology. 1994;210.
  15. Matias AB, Roselino AMF. Pemphigus and psychological stress: a review of the literature. Our Dermatol Online. 2013;4:616–8.
  16. Hertl M, Eming R, Veldman C. T cell control in autoimmune bullous skin disorders. J Clin Invest. 2006;116(5):1159–66.
  17. Kayani M, Aslam AM. Bullous pemphigoid and pemphigus vulgaris. BMJ. 2017;357:1–7.
  18. Leary FO, Samman S. Vitamin B12 in Health and Disease. Nutrients. 2010;2:299–316.
  19. Necas J, Bartosikova L, Brauner P, Kolar J. Hyaluronic acid ( hyaluronan ): a review. Vet Med (Praha). 2008;53(8):397–411.
  20. Fallacara A, Baldini E, Manfredini S, Vertuani S. Hyaluronic acid in the third millennium. Polymers (Basel). 2018;10(701):1–36.

How to Cite

Permatasari, D. K., & Hidayat, W. . (2023). A rare case of oral pemphigus vulgaris in teenager suspected induced by stress. Journal of Dentomaxillofacial Science, 8(1). https://doi.org/10.15562/jdmfs.v8i1.991

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