Irene Edith Rieuwpassa, Nurlindah Hamrun, St. Rahma Lukman, Reski Y. S, Soelistia Ramadhani
The study aimed to determine the effect of prickly pear cactus extract in inhibiting the growth of Staphylococcus
aureus, Streptococcus mutans and Candida albicans. The laboratory experimental study using diffusion method. The
concentration of the prickly pear cactus fruit extract used was 25%, 50%, 75%, 100%, whereas bacterial samples
derived from the laboratory of Microbiology, Faculty of Medicine, University of Hasanuddin. The observation of
several concentrations showed a decrease in the number of colonies contained S.aureus, S.mutans, C.albicans
significant with increasing concentrations of the prickly pear cactus fruit extract. From these observations, the
largest inhibitory concentration present in a concentration of 100%. The conclusion is the fruit of the prickly pear
cactus extract can inhibit the growth of S.aureus, S.mutans, and C.albicans. The higher the concentration of the
extract, the more reduced the growth of S.aureus colonies, S.mutans, and C.albicans and vice versa.